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A Talk on Cancer Metastasis
2:00 pm Sunday December 22, 2013 to 3:00 pm Sunday December 22, 2013
Central Department of Biotechnology, Tribhuvan University, TU Road, Kirtipur, Central Region, Nepal

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A Talk on Cancer Metastasis

We are pleased to invite you to Talk Program to be held on 22nd December, 2013 organized by Biotechnology Society of Nepal. This program is being organized in association with Central Department of Biotechnology, Tribhuvan University, Krtipur, Nepal & Science Development Initiative Nepal.

Details of The Program:

Title of the Talk : Identifying genes that contributes to cancer metastasis to the brain metastasis from primary breast tumours

Abstract:
Cancers that originate in one part of the body (primary tumours) can develop the ability to spread to other organs (metastasise) producing new, often fatal, secondary tumours, which we refer as metastasis. Tumour metastasis to the brain is a common and deadly development in certain cancers; 40-50 % of lung tumours and 15-20% of breasts tumours metastasise to the brain. Once a primary tumour has formed, additional changes to the DNA of the tumour cells are required before it can migrate to, and grow inside, the brain. The contribution that gene silencing through epigenetic mechanisms plays in metastasis to the brain is not well understood We are particularly interested in determining the role that gene promoter methylation (a common mechanism of gene deregulation in tumour formation) plays in primary tumour metastasis to the brain. We have screened genes for promoter methylation by Combined Bisulphite and Restriction Analysis (CoBRA) in metastatic brain tumours and their associated primary breast tumours.

During the talk, we will discuss the following:
The basics of cancer and metastasis
How DNA methylation works and contributes to tumour origin
Metastatic cascades and Metastatic brain tumours
Our Methodologies to study brain metastases
Findings, conclusions and future prospects

Speaker:
Rajendra Prasad Pangeni
PhD Candidate (Metastatic Brain Tumours)
University of Wolverhampton, UK
Life Time Member (Biotechnology Society of Nepal)
Active Member (Science Development Initiative - Nepal)
Student Ambassador for a year (June 2010 to July 2011).

PS: There will be a Thesis Defense of Mr. Suren Neupane at 1:00 P.M. to 2:00 PM , entitled "GENETIC DIVESITY ASSESSMENT OF SWERTIA CHIRAYITA [ROXB.EX FLEM] KARST POPULATIONS OF NEPAL USING ISSR TECHNIQUE AND DNA BARCODING AND PHYLOGENETIC ANALYSIS USING NUCLEAR AND CHLOROPLAST SEQUENCES". Thanks !!

For more info: http://facebook.com/262432240573946


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